Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098195 | 0.92 | MAPT (0.47) | MAPTCHRM2MEN1KMT2ATDP1 | |
| SCHEMBL7615058 | 0.84 | CHRM2 (0.51) | MAPTCHRM2MEN1KMT2ATDP1 | |
| SCHEMBL18236653 | 0.81 | CHRM2 (0.53) | MAPTCHRM2MEN1KMT2ATDP1 | |
| SCHEMBL6327499 | 0.77 | MAPT (0.56) | MAPTCHRM2MEN1KMT2ATDP1 | |
| SCHEMBL10632588 | 0.77 | CHRM2 (0.59) | MAPTCHRM2MEN1KMT2ATDP1 | |
| SCHEMBL16340151 | 0.76 | MAPT (0.51) | MAPTCHRM2MEN1KMT2ATDP1 | |
| SCHEMBL28587054 | 0.76 | ALDH1A1 (0.49) | MAPTCHRM2MEN1KMT2ATDP1 | |
| SCHEMBL7771131 | 0.76 | ALDH1A1 (0.47) | MAPTTDP1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL30994802 | 0.75 | CHRM2 (0.58) | MAPTCHRM2MEN1KMT2ATDP1 | |
| SCHEMBL1644887 | 0.75 | ALDH1A1 (0.50) | MAPTKMT2ATDP1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087709-A1 | N,N',N\"-triaryl-1,2,3-triaminopropane derivatives, process for their preparation and their use as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-07 | — | — | EP | disclosed |