Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10879974 | 0.90 | CYP19A1 (0.40) | CYP19A1CYP2C19 | |
| SCHEMBL11240205 | 0.90 | ACE (0.47) | CYP19A1CYP2C19 | |
| SCHEMBL10817392 | 0.90 | ACE (0.48) | — | |
| SCHEMBL11088900 | 0.90 | ACE (0.48) | — | |
| SCHEMBL10818819 | 0.87 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL11080471 | 0.85 | ACE (0.43) | — | |
| SCHEMBL10880216 | 0.79 | CYP19A1 (0.40) | CYP19A1CYP2C19ALDH1A1LMNA | |
| SCHEMBL10811706 | 0.79 | CYP19A1 (0.51) | CYP19A1CYP2C19ALDH1A1LMNA | |
| SCHEMBL10647022 | 0.77 | ACE (0.47) | — | |
| SCHEMBL10818844 | 0.76 | ALDH1A1 (0.53) | CYP19A1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093084-A1 | 1-Carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |