Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034688 | 0.86 | MAPK14 (0.36) | TSHRALDH1A1LMNAPPARGMAPK14 | |
| SCHEMBL8508478 | 0.83 | MEN1 (0.40) | TSHRLMNACYP1A2PPARGMAPK14 | |
| Hydrochloric Acid SCHEMBL10951678 | 0.82 | MEN1 (0.41) | TSHRLMNAPPARGMAPK14CNR1 | |
| SCHEMBL5520187 | 0.79 | TSHR (0.43) | TSHRALDH1A1LMNACYP1A2CNR1 | |
| SCHEMBL1967963 | 0.78 | TSHR (0.42) | TSHRALDH1A1LMNACYP1A2PPARG | |
| SCHEMBL10844188 | 0.78 | TSHR (0.42) | TSHRALDH1A1LMNACYP1A2PPARG | |
| SCHEMBL10640000 | 0.78 | TSHR (0.36) | TSHRALDH1A1LMNACYP1A2CNR1 | |
| SCHEMBL3369844 | 0.78 | TSHR (0.48) | TSHRALDH1A1LMNACYP1A2PPARG | |
| SCHEMBL4650648 | 0.77 | PPARG (0.40) | CYP1A2PPARGMEN1KMT2ARAB9A | |
| SCHEMBL28142396 | 0.74 | TSHR (0.42) | TSHRALDH1A1LMNACYP1A2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414391-A | A process for preparing 2-pyridinyloxyphenoxy-lower-alkanoates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-11-08 | — | — | US | disclosed |
| EP-0040478-A1 | Process for preparing pyridine derivatives and intermediates useful in the process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-11-25 | — | — | EP | disclosed |