SCHEMBL4650648

SCHEMBL4650648

CCC(OC)(Oc1ccccc1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.40
PPARA Q07869 7/20 0.40
ALOX15 P16050 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 2/20 0.37
RAB9A P51151 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 2/20 0.36
ADORA3 P0DMS8 1/20 0.36
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
KMT2A Q03164 1/20 0.36
CES1 P23141 1/20 0.36
RIPK1 Q13546 1/20 0.36
CA4 P22748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15333757 0.86 MAPT (0.38) PPARGPPARAALOX15NPSR1L3MBTL1
SCHEMBL5718637 0.80 PPARA (0.43) PPARGPPARAL3MBTL1CYP2C19
SCHEMBL11666473 0.80 PPARG (0.41) PPARGPPARAALOX15NPSR1L3MBTL1
SCHEMBL7593642 0.79 CES1 (0.43) PPARGL3MBTL1RAB9ACYP1A2CYP2D6
SCHEMBL11206142 0.77 TSHR (0.39) PPARGRAB9ACYP1A2MEN1KMT2A
SCHEMBL11485660 0.76 L3MBTL1 (0.44) PPARGPPARAL3MBTL1MAPTCYP1A2
SCHEMBL16965437 0.76 ALDH1A1 (0.35) CYP1A2CYP2D6CYP2C19MEN1KMT2A
SCHEMBL23754112 0.76 PPARG (0.45) PPARGPPARAALOX15NPSR1L3MBTL1
SCHEMBL36736 0.76 ALOX15 (0.45) PPARGPPARAALOX15L3MBTL1CYP1A2
SCHEMBL10567707 0.76 ALOX15 (0.41) PPARGPPARAALOX15MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3983424-A1 A MANUFACTURING PROCESS FOR PEPTIDE AND PROTEIN PRODUCTION Mytide Therapeutics, Inc. (US) 2022-04-20 EP disclosed
EP-1971222-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2008-09-24 EP disclosed
WO-2007059066-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2007-05-24 WO disclosed