SCHEMBL11206231

SCHEMBL11206231

NC(c1ccc(OCc2ccccc2)cc1)C(Cl)(Cl)Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 1/20 0.54
MAOA P21397 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
BCHE P06276 2/20 0.51
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
PTGS1 P23219 1/20 0.51
SLC6A2 P23975 1/20 0.51
CYP2C19 P33261 1/20 0.51
PTGS2 P35354 1/20 0.51
SLC6A3 Q01959 1/20 0.51
HIF1A Q16665 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
LTA4H P09960 1/20 0.51
ALOX5 P09917 1/20 0.48
PARP10 Q53GL7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30703580 0.85 MAOB (0.56) MAOBGAAMAPTMAOARAB9A
SCHEMBL11208737 0.83 MAOB (0.54) MAOBGAAMAPTMAOARAB9A
SCHEMBL10992484 0.81 LMNA (0.56) MAOBGAAMAPTMAOARAB9A
SCHEMBL11838902 0.80 MAOB (0.61) MAOBGAAMAPTMAOARAB9A
SCHEMBL322827 0.79 LMNA (0.58) MAOBGAAMAPTMAOARAB9A
SCHEMBL6568552 0.79 LMNA (0.58) MAOBGAAMAPTMAOARAB9A
SCHEMBL15499831 0.78 LMNA (0.61) MAOBGAAMAPTMAOARAB9A
SCHEMBL6376299 0.78 MAOB (0.59) MAOBGAAMAPTMAOARAB9A
SCHEMBL7768214 0.78 MAOB (0.59) MAOBGAAMAPTMAOARAB9A
SCHEMBL13292604 0.78 CYP1A2 (0.60) MAOBGAAMAPTMAOARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0051196-B1 4-BENZYLOXY-ALPHA-TRICHLOROMETHYLBENZYL AMINES, PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE BAYER AG (DE) 1983-11-09 EP claimed
EP-0051196-A1 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use BAYER AG (DE) 1982-05-12 EP claimed
EP-0051196-B1 4-BENZYLOXY-ALPHA-TRICHLOROMETHYLBENZYL AMINES, PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE BAYER AG (DE) 1983-11-09 EP disclosed
EP-0051196-B1 4-BENZYLOXY-ALPHA-TRICHLOROMETHYLBENZYL AMINES, PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE BAYER AG (DE) 1983-11-09 EP disclosed
EP-0051196-A1 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use BAYER AG (DE) 1982-05-12 EP disclosed
EP-0051196-A1 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use BAYER AG (DE) 1982-05-12 EP disclosed
EP-0051196-A1 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use BAYER AG (DE) 1982-05-12 EP disclosed