SCHEMBL11206339

SCHEMBL11206339

COC(=O)c1nscc1S(=O)(=O)N=C=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 2/20 0.33
STAT3 P40763 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9365220 0.85 KDM4E (0.37) NPSR1KDM4E
SCHEMBL9365314 0.77 CA2 (0.46) NPSR1KDM4ESTAT3HIF1A
SCHEMBL9364889 0.77 NPSR1 (0.39) NPSR1KDM4ESTAT3HIF1A
SCHEMBL10752945 0.74 CA1 (0.36) NPSR1KDM4E
SCHEMBL9364555 0.70
SCHEMBL6228599 0.70 EDNRA (0.46)
SCHEMBL6228820 0.69 CA1 (0.59) KDM4E
SCHEMBL7472808 0.68 CA1 (0.53)
SCHEMBL10756739 0.68 CA1 (0.36) KDM4E
SCHEMBL10756607 0.68 CA1 (0.33) NPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0095925-A2 Herbicidal imidazole, pyrazole, thiazole and isothiazole derivatives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-12-07 EP disclosed
EP-0008003-B1 (DL)-16-PHENOXY- AND 16-SUBSTITUTED PHENOXY-9-KETO PROSTATRIENOIC ACIDS AND DERIVATIVES AND PROCESSES FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL COMPOSITIONS SYNTEX (U.S.A.) INC. (US) 1983-02-09 EP disclosed