Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP4 | P49662 | 1/20 | 0.35 |
| ▸ | CASP5 | P51878 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11202845 | 0.99 | HTR2A (0.39) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11201445 | 0.84 | ESR1 (0.41) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11200114 | 0.84 | PRKCI (0.46) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| Hydrochloric Acid SCHEMBL11197387 | 0.82 | PRKCI (0.45) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11204218 | 0.82 | KDM4E (0.41) | HTR2AKDM4EALDH1A1HTR2CHRH1 | |
| Hydrochloric Acid SCHEMBL11198496 | 0.81 | KDM4E (0.40) | HTR2AKDM4EALDH1A1HTR2CHRH1 | |
| SCHEMBL11197339 | 0.81 | HTR2C (0.39) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11203370 | 0.79 | IKBKB (0.40) | HTR2AKDM4EALDH1A1HTR2CKHK | |
| SCHEMBL11205242 | 0.77 | MAPT (0.45) | KDM4EALDH1A1SMN1; SMN2CASP1TSHR | |
| SCHEMBL11200202 | 0.77 | KHK (0.38) | HTR2AKDM4EALDH1A1HTR2CKHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |