Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197538 | 0.86 | PRKCI (0.41) | ESR1SYKKHKHRH4HTR3A | |
| SCHEMBL11201137 | 0.85 | ESR1 (0.39) | ESR1HRH4HTR2AHTR3AALDH1A1 | |
| SCHEMBL11206366 | 0.84 | HTR2A (0.39) | ESR1KHKHRH4HTR2AALDH1A1 | |
| SCHEMBL11200579 | 0.84 | SYK (0.40) | ESR1SYKKHKCCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL11202845 | 0.83 | HTR2A (0.39) | ESR1KHKHRH4HTR2AALDH1A1 | |
| SCHEMBL11202898 | 0.79 | ELANE (0.35) | ESR1KHKHRH4HTR2AHTR2C | |
| SCHEMBL11204218 | 0.77 | KDM4E (0.41) | HTR2AALDH1A1KDM4EHTR2CUSP2 | |
| Hydrochloric Acid SCHEMBL11198496 | 0.76 | KDM4E (0.40) | HTR2AALDH1A1KDM4EHTR2CUSP2 | |
| SCHEMBL11201871 | 0.75 | PRKCI (0.41) | ESR1KHKHTR2AHTR2C | |
| SCHEMBL11205170 | 0.74 | ALDH1A1 (0.42) | SYKKHKHRH4HTR3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |