Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.60 |
| ▸ | MAPT | P10636 | 11/20 | 0.60 |
| ▸ | USP2 | O75604 | 4/20 | 0.60 |
| ▸ | CRHBP | P24387 | 3/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.60 |
| ▸ | IDE | P14735 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329711 | 0.78 | MEN1 (0.81) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL11329714 | 0.78 | MEN1 (0.81) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL10474484 | 0.74 | MAPT (0.71) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL10474485 | 0.74 | MAPT (0.71) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL11205772 | 0.73 | MEN1 (0.62) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL11851144 | 0.73 | MEN1 (0.64) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL10580923 | 0.72 | MAPT (0.76) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL10580918 | 0.72 | MAPT (0.76) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL11320980 | 0.71 | MEN1 (0.89) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL7697693 | 0.71 | MEN1 (0.62) | MEN1KMT2AMAPTUSP2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012020-B1 | DRY SILVER PHOTO-SENSITIVE COMPOSITIONS, DYES FOR USE THEREIN AND PREPARATION OF SUCH DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4283487-A | Thermolabile acutance dyes for dry silver | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| EP-0018830-A2 | Spirobenzofuranones, their production and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-11-12 | — | — | EP | disclosed |
| WO-1980001213-A1 | DRY SILVER PHOTO-SENSITIVE COMPOSITIONS,DYES FOR USE THEREIN AND PREPARATION OF SUCH DYES | MINNESOTA MINING & MFG (GB) | 1980-06-12 | — | — | WO | disclosed |
| EP-0012020-A1 | Dry silver photo-sensitive compositions, dyes for use therein and preparation of such dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1980-06-11 | — | — | EP | disclosed |