Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205148 | 0.94 | LDHA (0.54) | TDP1L3MBTL1MAPK1ALDH1A1TSHR | |
| SCHEMBL7641920 | 0.93 | KMT2A (0.51) | TDP1L3MBTL1MAPK1ALDH1A1TSHR | |
| SCHEMBL28126623 | 0.91 | KMT2A (0.57) | TDP1L3MBTL1MAPK1ALDH1A1TSHR | |
| SCHEMBL9670491 | 0.91 | TDP1 (0.57) | TDP1L3MBTL1MAPK1ALDH1A1TSHR | |
| SCHEMBL11246312 | 0.90 | KMT2A (0.49) | TDP1L3MBTL1MAPK1ALDH1A1TSHR | |
| SCHEMBL1237067 | 0.87 | GLA (0.54) | ALDH1A1KMT2AGLAALOX5CALM1 | |
| SCHEMBL1238474 | 0.87 | GLA (0.54) | ALDH1A1KMT2AGLAALOX5CALM1 | |
| SCHEMBL8710489 | 0.87 | KMT2A (0.54) | TDP1L3MBTL1MAPK1ALDH1A1TSHR | |
| SCHEMBL11205643 | 0.86 | MEN1 (0.65) | TDP1L3MBTL1MAPK1ALDH1A1TSHR | |
| SCHEMBL1238406 | 0.85 | KMT2A (0.52) | ALDH1A1KMT2AGLAALOX5CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |