Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137604 | 0.83 | DNMT1 (0.55) | WDR5TYMSHPGDKDM4EALDH1A1 | |
| SCHEMBL29423627 | 0.83 | DNMT1 (0.55) | WDR5TYMSHPGDKDM4EALDH1A1 | |
| SCHEMBL29262283 | 0.81 | DNMT1 (0.53) | WDR5TYMSHPGDKDM4EALDH1A1 | |
| SCHEMBL8603656 | 0.81 | SOS1 (0.52) | WDR5TYMSHPGDKDM4EALDH1A1 | |
| SCHEMBL7883029 | 0.76 | TYMS (0.47) | WDR5TYMSHPGDKDM4EALDH1A1 | |
| Maleic Anhydride SCHEMBL29199820 | 0.75 | DNMT1 (0.47) | WDR5TYMSHPGDKDM4EALDH1A1 | |
| SCHEMBL15119562 | 0.75 | ALDH1A1 (0.59) | TYMSHPGDKDM4EALDH1A1SOS1 | |
| SCHEMBL475904 | 0.74 | TYMS (0.61) | TYMSKDM4EALDH1A1SOS1NR4A1 | |
| SCHEMBL9061416 | 0.73 | HSD17B10 (0.56) | WDR5TYMSHPGDKDM4EALDH1A1 | |
| SCHEMBL17256684 | 0.73 | TTR (0.45) | TYMSKDM4EALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083484-A1 | 1,1-Alkanediol dicarboxylate linked antibacterial agents | PFIZER INC. (US) | 1983-07-13 | — | — | EP | disclosed |