Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456655 | 0.93 | TSHR (0.47) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL3748655 | 0.93 | TSHR (0.47) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL32686846 | 0.91 | TSHR (0.50) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| Ethylene Glycol SCHEMBL1931733 | 0.87 | TSHR (0.42) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL25427 | 0.85 | TSHR (0.41) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL1326102 | 0.85 | TSHR (0.41) | TSHRALDH1A1CYP3A4ATMHCAR2 | |
| SCHEMBL2418959 | 0.85 | TSHR (0.60) | TSHRLMNAALDH1A1CYP3A4ATM | |
| SCHEMBL10602340 | 0.85 | TSHR (0.60) | TSHRLMNAALDH1A1CYP3A4ATM | |
| Cyclopropane SCHEMBL1979200 | 0.85 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL2418958 | 0.85 | TSHR (0.60) | TSHRLMNAALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020529-B1 | PHOTOPOLYMERIZED HYDROPHILIC INTERPOLYMERS OF UNSATURATED CARBOXYLIC ACID AND ESTERS | The B.F. GOODRICH Company (US) | 1983-02-16 | — | — | EP | disclosed |