Cyclopropane

Cyclopropane

SCHEMBL1979200

C/C=C(\C)C(=O)OCCO.C1CC1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.32
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285423 0.94 TSHR (0.43) TSHRACHEALDH1A1THRBMGLL
SCHEMBL15637 0.94 TSHR (0.43) TSHRACHEALDH1A1THRBMGLL
SCHEMBL28569697 0.94 TSHR (0.43) TSHRACHEALDH1A1THRBMGLL
SCHEMBL5870616 0.91 TSHR (0.41) TSHRACHEALDH1A1THRBMGLL
SCHEMBL11207343 0.85 TSHR (0.42) TSHRALDH1A1
Ethylene Glycol SCHEMBL5974618 0.85 THRB (0.38) TSHRALDH1A1THRB
SCHEMBL28087290 0.82 THRB (0.52) TSHRACHEALDH1A1THRB
SCHEMBL6278553 0.82 TSHR (0.44) TSHRACHETHRB
SCHEMBL418569 0.82 THRB (0.41) TSHRALDH1A1THRB
SCHEMBL2340826 0.82 THRB (0.41) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871843-B2 Halogen-free flame retardant material APPLE INC. (US) 2014-10-28 US disclosed
US-20110144244-A1 HALOGEN-FREE FLAME RETARDANT MATERIAL APPLE INC. (US) 2011-06-16 US disclosed
CN-1312754-C FOrmation of air-gap SHIPLEY CO LLC (US) 2007-04-25 CN disclosed
CN-1510723-A Electronic device manufacture ϣ 2004-07-07 CN disclosed
CN-1495877-A FOrmation of air-gap ϣ 2004-05-12 CN disclosed