Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909869 | 0.98 | TSHR (0.57) | TSHRALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL24653168 | 0.86 | TSHR (0.53) | TSHRALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL20827819 | 0.86 | TSHR (0.47) | TSHRALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL9643771 | 0.85 | TSHR (0.65) | TSHRALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL8912811 | 0.84 | MGAM (0.50) | TSHRALDH1A1POLBLMNAKDM4E | |
| SCHEMBL11852921 | 0.84 | — | — | |
| SCHEMBL2373233 | 0.84 | MGAM (0.50) | TSHRALDH1A1POLBLMNAKDM4E | |
| SCHEMBL3966571 | 0.84 | MGAM (0.50) | TSHRALDH1A1POLBLMNAKDM4E | |
| SCHEMBL13113224 | 0.84 | POLB (0.55) | TSHRALDH1A1POLBLMNAHSD17B10 | |
| SCHEMBL14305160 | 0.81 | KDM4E (0.53) | TSHRALDH1A1POLBLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079920-A1 | NEW AZA-CROWN-ETHERS AND THEIR USE. | BORREGAARD IND (NO) | 1983-06-01 | — | — | EP | disclosed |
| WO-1982004253-A1 | NEW AZA-CROWN-ETHERS AND THEIR USE | DALE JOHANNES | 1982-12-09 | — | — | WO | disclosed |