SCHEMBL2373233

SCHEMBL2373233

CCOC(=O)CN1CCN(CC(=O)OCC)CC1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.50
GAA P10253 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
GSK3A P49840 2/20 0.48
GSK3B P49841 2/20 0.48
ALDH1A1 P00352 5/20 0.46
TRPA1 O75762 1/20 0.46
ELANE P08246 1/20 0.46
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 1/20 0.44
PIN1 Q13526 1/20 0.43
PIN4 Q9Y237 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
TSHR P16473 1/20 0.43
PKM P14618 1/20 0.42
HTR1A P08908 1/20 0.41
HTR2C P28335 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11852921 1.00
SCHEMBL3966571 1.00 MGAM (0.50) MGAMGAASIMGAM2GSK3A
SCHEMBL8912811 1.00 MGAM (0.50) MGAMGAASIMGAM2GSK3A
SCHEMBL689078 0.94 LMNA (0.45) MGAMGAASIMGAM2GSK3A
SCHEMBL8260387 0.94 MEN1 (0.47) MGAMGAASIMGAM2GSK3A
SCHEMBL29419289 0.94 ALDH1A1 (0.45) MGAMGAASIMGAM2GSK3A
SCHEMBL15997367 0.92 HSD17B10 (0.44) MGAMGAASIMGAM2GSK3A
SCHEMBL1127888 0.92 ALDH1A1 (0.45) MGAMGAASIMGAM2GSK3A
SCHEMBL8911750 0.92 HSD17B10 (0.44) MGAMGAASIMGAM2GSK3A
SCHEMBL65358 0.91 ALDH1A1 (0.46) MGAMGAASIMGAM2GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
EP-2552638-B1 NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER 3M INNOVATIVE PROPERTIES CO (US) 2015-04-22 EP disclosed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US disclosed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP disclosed
US-8535559-B2 Nitrogen-containing fluoroketones for high temperature heat transfer 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-09-17 US disclosed
EP-2552638-A1 NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER 3M Innovative Properties Company (US) 2013-02-06 EP disclosed
US-20110232870-A1 NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER 3M INNOVATION PROPERTIES COMPANY 2011-09-29 US disclosed
WO-2011119456-A1 NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110232870-A1 NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER FN3KRP, HSF1, NEK1 MGAM 2009/4885GAA 3944/4885SI 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.