Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945913 | 0.97 | KDM4E (0.55) | KDM4EHTTMAPTATMNPC1 | |
| SCHEMBL10942599 | 0.93 | KDM4E (0.46) | KDM4EHTTMAPTATMNPC1 | |
| SCHEMBL9761569 | 0.90 | KDM4E (0.68) | KDM4EHTTMAPTNPC1RAB9A | |
| SCHEMBL10948436 | 0.90 | KDM4E (0.46) | KDM4EHTTMAPTATMNPC1 | |
| SCHEMBL10944265 | 0.85 | KDM4E (0.51) | KDM4EHTTMAPTATMNPC1 | |
| SCHEMBL10947886 | 0.85 | KDM4E (0.51) | KDM4EHTTMAPTATMNPC1 | |
| SCHEMBL10945099 | 0.85 | KDM4E (0.51) | KDM4EHTTMAPTATMNPC1 | |
| SCHEMBL10945675 | 0.83 | KDM4E (0.51) | KDM4EHTTMAPTATMNPC1 | |
| SCHEMBL10941821 | 0.83 | ALDH1A1 (0.59) | KDM4EMAPTNPC1MEN1KMT2A | |
| SCHEMBL10943228 | 0.83 | KDM4E (0.51) | KDM4EHTTMAPTATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |