Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16747596 | 1.00 | ALOX5 (0.53) | ALOX5HTTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2414473 | 0.98 | ALOX5 (0.50) | ALOX5HTTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4201139 | 0.84 | — | — | |
| SCHEMBL11801520 | 0.82 | ALOX5 (0.55) | ALOX5HTTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL17779527 | 0.82 | ALOX5 (0.59) | ALOX5ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24354392 | 0.82 | ALOX5 (0.59) | ALOX5ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15177351 | 0.82 | ALOX5 (0.55) | ALOX5HTTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21972780 | 0.82 | ALOX5 (0.59) | ALOX5ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11414522 | 0.82 | ALOX5 (0.59) | ALOX5ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3491458 | 0.82 | ALOX5 (0.59) | ALOX5ALDH1A1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015604-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN INHIBITION OF LIPOGENESIS IN MAMMALS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-02-23 | — | — | EP | disclosed |
| EP-0015604-A1 | Compounds and compositions for use in inhibition of lipogenesis in mammals | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-09-17 | — | — | EP | disclosed |
| US-4202902-A | VETERINARY MEDICINE | SHELL OIL COMPANY (US) | 1980-05-13 | — | — | US | disclosed |