Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790690 | 0.96 | TAAR1 (0.38) | TAAR1PARP1MAPTLMNAHSD17B10 | |
| SCHEMBL11207361 | 0.83 | ACP1 (0.42) | TAAR1PARP1MAPTLMNAHSD17B10 | |
| SCHEMBL10794288 | 0.82 | POLB (0.37) | TAAR1PARP1LMNAKMT2AACP1 | |
| SCHEMBL11212853 | 0.76 | EGFR (0.44) | TAAR1LMNAHTTEGFR | |
| SCHEMBL11293787 | 0.75 | TAAR1 (0.48) | TAAR1MAPTLMNAHSD17B10MEN1 | |
| SCHEMBL11205811 | 0.75 | TAAR1 (0.32) | TAAR1MAPTLMNAHSD17B10MEN1 | |
| SCHEMBL11210047 | 0.74 | PARP1 (0.41) | TAAR1PARP1MAPTACP1ALOX5 | |
| SCHEMBL10792750 | 0.74 | CDC7 (0.39) | TAAR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL11205137 | 0.73 | PARP1 (0.36) | TAAR1PARP1ACP1ALOX5CYP3A4 | |
| SCHEMBL10551020 | 0.73 | TAAR1 (0.36) | TAAR1PARP1MAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034474-B1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Farmos-Yhtyma Oy (FI) | 1983-01-26 | — | — | EP | disclosed |
| US-4333947-A | HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES | FARMOS-YHTYMA OY (FI) | 1982-06-08 | — | — | US | disclosed |