Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139922 | 1.00 | IDO1 (0.54) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11207971 | 1.00 | IDO1 (0.54) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3129203 | 0.85 | MAPK1 (0.56) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3129207 | 0.85 | MAPK1 (0.56) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1176176 | 0.83 | CYP2C19 (0.41) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23171281 | 0.81 | HPGD (0.44) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10632150 | 0.81 | HPGD (0.44) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3144556 | 0.78 | ALDH1A1 (0.47) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3144562 | 0.78 | ALDH1A1 (0.47) | IDO1HPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10953999 | 0.78 | MAPT (0.45) | HPGDMAPTSMN1; SMN2RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025908-B1 | 1:1-NICKEL COMPLEXES AND THEIR USE | BASF Aktiengesellschaft (DE) | 1983-08-17 | — | — | EP | disclosed |
| EP-0025908-A1 | 1:1-Nickel complexes and their use | BASF Aktiengesellschaft (DE) | 1981-04-01 | — | — | EP | disclosed |