Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205557 | 0.86 | TDP1 (0.45) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL11197086 | 0.86 | TDP1 (0.45) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL11163305 | 0.86 | TDP1 (0.45) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL11202392 | 0.85 | TDP1 (0.44) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL10554944 | 0.84 | MEN1 (0.69) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL10992142 | 0.84 | MEN1 (0.43) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL16959467 | 0.84 | ALDH1A1 (0.46) | MEN1KMT2ATTRTDP1HPGD | |
| SCHEMBL10967020 | 0.84 | MEN1 (0.51) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL2075313 | 0.83 | KDM4E (0.47) | MEN1KMT2ATTRTDP1ALDH1A1 | |
| SCHEMBL10454825 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2ATTRTDP1PPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077963-A1 | 2-Nitro-5-(4-trifluoromethyl-phenoxy)-benzyl derivatives, process for their preparation, and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1983-05-04 | — | — | EP | disclosed |
| EP-0077961-A2 | Substituted 2-nitro-5-(4-trifluoromethyl-phenoxy) toluols, process for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1983-05-04 | — | — | EP | disclosed |