Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | GALR3 | O60755 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730702 | 0.97 | SMN1; SMN2 (0.68) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL1975340 | 0.97 | HRH1 (0.70) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL9803306 | 0.90 | HRH1 (0.62) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL10494023 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL28998684 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL29274355 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL8422457 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL1090112 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL28625836 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2TDP1HRH1MEN1 | |
| SCHEMBL821899 | 0.87 | MEN1 (0.59) | SMN1; SMN2USP2TDP1HRH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9702001-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-4317911-A | LIGHT STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1982-03-02 | — | — | US | disclosed |