Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975340 | 0.93 | HRH1 (0.70) | HRH1SMN1; SMN2USP2TDP1MAPK1 | |
| SCHEMBL11208162 | 0.90 | SMN1; SMN2 (0.71) | HRH1SMN1; SMN2USP2TDP1MAPK1 | |
| SCHEMBL9730702 | 0.87 | SMN1; SMN2 (0.68) | HRH1SMN1; SMN2USP2TDP1MAPK1 | |
| Triethylenemelamine SCHEMBL8359 | 0.85 | HRH1 (0.52) | HRH1SMN1; SMN2USP2TDP1MAPK1 | |
| SCHEMBL17351867 | 0.80 | HRH1 (0.77) | HRH1SMN1; SMN2USP2TDP1MAPK1 | |
| SCHEMBL9224600 | 0.80 | HRH1 (0.56) | HRH1SMN1; SMN2USP2TDP1MAPK1 | |
| SCHEMBL12341499 | 0.80 | HRH4 (0.50) | HRH1SMN1; SMN2USP2TDP1MAPK1 | |
| SCHEMBL9073359 | 0.80 | HRH1 (0.56) | HRH1SMN1; SMN2USP2TDP1MAPK1 | |
| SCHEMBL3027569 | 0.80 | HRH4 (0.50) | HRH1SMN1; SMN2USP2TDP1ALDH1A1 | |
| SCHEMBL1090112 | 0.78 | SMN1; SMN2 (0.58) | HRH1SMN1; SMN2USP2TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985584-A | RING OPENING REACTION WITH N2O4 OR N2O5 | SECRETARY OF STATE FOR DEFENCE (GB) | 1991-01-15 | — | — | US | claimed |
| EP-0223440-B1 | A PROCESS FOR THE PRODUCTION OF HIGH ENERGY MATERIAL | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1991-03-06 | — | — | EP | disclosed |
| US-4985584-A | RING OPENING REACTION WITH N2O4 OR N2O5 | SECRETARY OF STATE FOR DEFENCE (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0223440-A1 | A process for the production of high energy material | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1987-05-27 | — | — | EP | disclosed |