Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93601 | 0.85 | MAPT (0.69) | NPC1RAB9AMAPTHPGDKDM4E | |
| SCHEMBL11218165 | 0.83 | NPC1 (0.55) | NPC1RAB9AMAPTHPGDKDM4E | |
| SCHEMBL30506538 | 0.83 | NPC1 (0.55) | NPC1RAB9AMAPTHPGDKDM4E | |
| SCHEMBL29215654 | 0.83 | NPC1 (0.55) | NPC1RAB9AMAPTHPGDKDM4E | |
| SCHEMBL5134949 | 0.81 | KMT2A (0.59) | NPC1RAB9AMAPTHPGDKDM4E | |
| SCHEMBL11206662 | 0.79 | RAB9A (0.50) | NPC1RAB9AMAPTHPGDKDM4E | |
| SCHEMBL11214191 | 0.78 | MAPT (0.53) | MAPTHPGDKDM4EALDH1A1ALOX15 | |
| SCHEMBL11213945 | 0.78 | MAPT (0.57) | NPC1RAB9AMAPTHPGDKDM4E | |
| SCHEMBL11213117 | 0.78 | NPC1 (0.50) | NPC1RAB9AMAPTHPGDKDM4E | |
| SCHEMBL93245 | 0.78 | MAPT (0.79) | NPC1RAB9AMAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079141-A1 | Aminoresorcinol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-05-18 | — | — | EP | disclosed |