Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28924404 | 1.00 | THRB (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL10008072 | 1.00 | THRB (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL11354124 | 1.00 | THRB (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL31286358 | 0.95 | TSHR (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL9547073 | 0.95 | TSHR (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL31286343 | 0.95 | TSHR (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL11349951 | 0.95 | THRB (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL2492197 | 0.95 | TSHR (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL11361004 | 0.95 | TSHR (0.40) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL31286379 | 0.95 | TSHR (0.40) | THRBTSHRMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253934-A | Rubber composition and high-hardness low-creep rubber prepared from same | 北京中铁科新材料技术有限公司 | 2023-06-13 | — | — | CN | claimed |
| CN-116253934-A | Rubber composition and high-hardness low-creep rubber prepared from same | 北京中铁科新材料技术有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-0017734-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING CARBON BLACK, METHOD FOR PREPARING THE SAME AND METHOD FOR CURING THE COMPOSITIONS | SWS Silicones Corporation (US) | 1983-04-13 | — | — | EP | disclosed |
| EP-0002745-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING TITANIUM ESTERS | SWS Silicones Corporation (US) | 1981-11-25 | — | — | EP | disclosed |
| EP-0017734-A1 | Curable organopolysiloxane compositions containing carbon black, method for preparing the same and method for curing the compositions | SWS Silicones Corporation (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4221693-A | ROOM TEMPERATURE VULCANIZED SILICONE RUBBERS | WACKER SILICONES CORPORATION | 1980-09-09 | — | — | US | disclosed |
| EP-0002745-A1 | Curable organopolysiloxane compositions containing titanium esters | SWS Silicones Corporation (US) | 1979-07-11 | — | — | EP | disclosed |
| US-4111890-A | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING TITANIUM ESTERS | SWS SILICONES CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |