Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 10/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TK1 | P04183 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208268 | 1.00 | TK2 (0.53) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11289214 | 0.94 | TK2 (0.55) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11289213 | 0.94 | TK2 (0.55) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11205705 | 0.91 | CYP1A2 (0.50) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11205706 | 0.91 | CYP1A2 (0.50) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11210993 | 0.91 | TK1 (0.56) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11210991 | 0.91 | TK1 (0.56) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11208264 | 0.89 | CYP1A2 (0.52) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11291366 | 0.88 | CYP1A2 (0.55) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL11286833 | 0.88 | CYP1A2 (0.55) | TK2CYP1A2CYP3A4TSHRTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095294-A1 | Deoxyuridine compounds, methods for preparing them and their use in medicine | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | claimed |
| EP-0095294-A1 | Deoxyuridine compounds, methods for preparing them and their use in medicine | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |