SCHEMBL11208274

SCHEMBL11208274

COC(=O)/C=C/c1ccc(OC(C)(C)C)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
TYR P14679 1/20 0.62
CA7 P43166 1/20 0.62
CA9 Q16790 1/20 0.62
CA14 Q9ULX7 1/20 0.62
PTPN1 P18031 1/20 0.54
MAPT P10636 3/20 0.54
KDM4E B2RXH2 3/20 0.54
TTR P02766 1/20 0.53
APP P05067 1/20 0.53
GSK3B P49841 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
HDAC3 O15379 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11208276 1.00 CA12 (0.62) CA12CA1CA2TYRCA7
SCHEMBL19244300 0.87 ESR1 (0.51) CA12CA1CA2TYRCA7
SCHEMBL19244302 0.87 ESR1 (0.51) CA12CA1CA2TYRCA7
SCHEMBL27554910 0.85 CA12 (0.60) CA12CA1CA2TYRCA7
SCHEMBL27554909 0.85 CA12 (0.60) CA12CA1CA2TYRCA7
SCHEMBL71224 0.84 CA12 (0.84) CA12CA1CA2TYRCA7
SCHEMBL5057418 0.84 CA12 (0.84) CA12CA1CA2TYRCA7
SCHEMBL10390641 0.83 GLA (0.53) MAPTAPPGSK3BMEN1KMT2A
SCHEMBL15805571 0.83 THRB (0.66) CA12CA1CA2TYRCA7
SCHEMBL10390643 0.83 GLA (0.53) MAPTAPPGSK3BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795327-B Resin composition and optical compensation film using the same 东曹株式会社 2019-08-30 CN disclosed
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP disclosed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US disclosed
US-20170242174-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORPORATION (JP) 2017-08-24 US disclosed
EP-3208301-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME Tosoh Corporation (JP) 2017-08-23 EP disclosed
CN-106795327-A Resin composition and optical compensation film using the same 东曹株式会社 2017-05-31 CN disclosed
US-4399297-A Polyalkoxycarbinol cinnamates and protective sun agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1983-08-16 US disclosed