Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530424 | 0.97 | TSHR (0.40) | TSHRLMNAESR1ESR2THRB | |
| Phosphine SCHEMBL28207799 | 0.94 | TSHR (0.39) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Ammonia Solution, Strong SCHEMBL976790 | 0.93 | TSHR (0.38) | TSHRLMNAESR1ESR2THRB | |
| SCHEMBL29218396 | 0.90 | TSHR (0.41) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| SCHEMBL11021218 | 0.90 | TSHR (0.35) | TSHRLMNAESR1ESR2THRB | |
| Phosphine SCHEMBL1535966 | 0.88 | TSHR (0.47) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Ammonia Solution, Strong SCHEMBL11364094 | 0.88 | TSHR (0.39) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Phosphine SCHEMBL10694267 | 0.88 | TSHR (0.47) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| SCHEMBL8601485 | 0.87 | TSHR (0.44) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| SCHEMBL10430444 | 0.85 | TSHR (0.44) | TSHRTHRBSLC22A1FDPSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405766-A | Phosphonium bicarbonate catalysts for promoting reaction of epoxides with carboxylic acids or anhydrides | THE DOW CHEMICAL COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| US-4284573-A | Preparation of glycidyl ethers | THE DOW CHEMICAL COMPANY (US) | 1981-08-18 | — | — | US | disclosed |