Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 7/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704949 | 0.97 | TSHR (0.50) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| SCHEMBL29218396 | 0.97 | TSHR (0.41) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Ammonia Solution, Strong SCHEMBL1697449 | 0.94 | TSHR (0.47) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Phosphine SCHEMBL1535966 | 0.94 | TSHR (0.47) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Phosphine SCHEMBL10694267 | 0.94 | TSHR (0.47) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Ammonia Solution, Strong SCHEMBL2210353 | 0.94 | TSHR (0.47) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Ammonia Solution, Strong SCHEMBL11364094 | 0.94 | TSHR (0.39) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Ammonia Solution, Strong SCHEMBL2315629 | 0.94 | TSHR (0.47) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Ammonia Solution, Strong SCHEMBL11212815 | 0.94 | TSHR (0.47) | TSHRTHRBSLC22A1SLC22A2FDPS | |
| Phosphine SCHEMBL28207799 | 0.94 | TSHR (0.39) | TSHRTHRBSLC22A1SLC22A2FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000395-A1 | ADDITIVES WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYURETHANE AND POLYISOCYANURATE FOAM FORMULATIONS DURING POLYMERIZATION | ALLIED-SIGNAL INC. (US) | 1993-01-07 | — | — | WO | claimed |
| US-5137929-A | Additives which stabilize hydrohalocarbon blowing agent in polyurethane and polyisocyanurate foam formulations during polymerization | ALLIED-SIGNAL INC. (US) | 1992-08-11 | — | — | US | claimed |
| EP-0942033-A2 | HCFC-141b blown PU foams with low levels of HCFC-113a by-products | Bayer Corporation (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5849807-A | HCFC-141b blown foams with low levels of HCFC-1131a by-products | BAYER CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| US-5464560-A | Polyurethanes | BAYER CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| US-5407596-A | Polyols for the production of foams with HCFC blowing agents | MILES INC. (US) | 1995-04-18 | — | — | US | disclosed |
| WO-1993000395-A1 | ADDITIVES WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYURETHANE AND POLYISOCYANURATE FOAM FORMULATIONS DURING POLYMERIZATION | ALLIED-SIGNAL INC. (US) | 1993-01-07 | — | — | WO | disclosed |
| US-5137929-A | Additives which stabilize hydrohalocarbon blowing agent in polyurethane and polyisocyanurate foam formulations during polymerization | ALLIED-SIGNAL INC. (US) | 1992-08-11 | — | — | US | disclosed |