Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | APLNR | P35414 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901126 | 0.97 | AGTR1 (0.54) | C5AR1MC4RAGTR1EPHA2AGTR2 | |
| Saralasin SCHEMBL23 | 0.94 | C5AR1 (0.59) | C5AR1MC4RAGTR1EPHA2AGTR2 | |
| Saralasin SCHEMBL18699973 | 0.94 | C5AR1 (0.59) | C5AR1MC4RAGTR1EPHA2AGTR2 | |
| Saralasin SCHEMBL2199404 | 0.93 | C5AR1 (0.58) | C5AR1MC4RAGTR1EPHA2AGTR2 | |
| SCHEMBL34470213 | 0.93 | C5AR1 (0.60) | C5AR1MC4RAGTR1EPHA2AGTR2 | |
| Saralasin SCHEMBL125013 | 0.93 | C5AR1 (0.58) | C5AR1AGTR1EPHA2AGTR2APLNR | |
| SCHEMBL19780882 | 0.92 | C5AR1 (0.60) | C5AR1MC4RAGTR1EPHA2AGTR2 | |
| Saralasin SCHEMBL2200145 | 0.92 | C5AR1 (0.57) | C5AR1AGTR1EPHA2AGTR2APLNR | |
| SCHEMBL11022870 | 0.92 | AGTR1 (0.53) | C5AR1MC4RAGTR1EPHA2AGTR2 | |
| SCHEMBL11023111 | 0.91 | AGTR1 (0.61) | C5AR1AGTR1EPHA2AGTR2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034260-B1 | PEPTIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS OR DIAGNOSTIC AGENTS CONTAINING THEM | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1983-07-20 | — | — | EP | disclosed |
| US-3915948-A | Sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-proline | NORWICH EATON PHARMACEUTICALS, INC., A CORP. OF OH | 1975-10-28 | — | — | US | disclosed |