Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.52 |
| ▸ | CA2 | P00918 | 7/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CA11 | O75493 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211404 | 0.91 | CA1 (0.50) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11207574 | 0.84 | LMNA (0.48) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL11207490 | 0.81 | CA1 (0.43) | CA1CA2PTPRBPI4KB | |
| SCHEMBL11207437 | 0.78 | CA1 (0.40) | CA1CA2PTPRBPI4KB | |
| SCHEMBL11205053 | 0.77 | CA1 (0.40) | CA1CA2PTPRBPI4KB | |
| SCHEMBL22017475 | 0.77 | PI4KB (0.42) | CA1CA2PTPRBPI4KB | |
| SCHEMBL11204633 | 0.77 | PI4KB (0.42) | CA1CA2PTPRBPI4KB | |
| SCHEMBL11202473 | 0.76 | PI4KB (0.39) | CA1CA2SMN1; SMN2PTPRBPI4KB | |
| SCHEMBL11071626 | 0.73 | PI4KB (0.39) | CA1CA2PTPRBPI4KB | |
| SCHEMBL11081890 | 0.73 | PI4KB (0.39) | CA1CA2PTPRBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |