Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10886613 | 0.99 | ALB (0.50) | ALBLMNAMTORALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL10886607 | 0.99 | ALB (0.50) | ALBLMNAMTORALDH1A1THRB | |
| SCHEMBL2585673 | 0.91 | ALB (0.51) | ALBLMNAMTORALDH1A1THRB | |
| SCHEMBL207772 | 0.89 | LMNA (0.62) | ALBLMNAMTORALDH1A1THRB | |
| SCHEMBL21423108 | 0.89 | LMNA (0.62) | ALBLMNAMTORALDH1A1THRB | |
| SCHEMBL5697575 | 0.89 | LMNA (0.62) | ALBLMNAMTORALDH1A1THRB | |
| SCHEMBL547089 | 0.89 | LMNA (0.62) | ALBLMNAMTORALDH1A1THRB | |
| SCHEMBL1230711 | 0.89 | LMNA (0.62) | ALBLMNAMTORALDH1A1THRB | |
| SCHEMBL16805415 | 0.89 | LMNA (0.62) | ALBLMNAMTORALDH1A1THRB | |
| SCHEMBL4286246 | 0.89 | LMNA (0.62) | ALBLMNAMTORALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010205-B1 | 5-SUBSTITUTED 1-(2'-DEOXY-2'-SUBSTITUTED-BETA-D-ARABINOFURANOSYL) PYRIMIDINE NUCLEOSIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Sloan-Kettering Institute For Cancer Research (US) | 1983-05-04 | — | — | EP | claimed |