Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120895 | 0.94 | NR3C1 (0.43) | NR3C1PGRNR3C2AR | |
| Hydrochloric Acid SCHEMBL1120919 | 0.93 | NR3C1 (0.42) | NR3C1PGRNR3C2AR | |
| Hydrochloric Acid SCHEMBL1120816 | 0.87 | NR3C1 (0.41) | NR3C1PGRNR3C2AR | |
| Hydrochloric Acid SCHEMBL1120878 | 0.85 | NR3C1 (0.43) | NR3C1PGRNR3C2AR | |
| Hydrochloric Acid SCHEMBL5430641 | 0.84 | NR3C1 (0.43) | NR3C1PGRNR3C2AR | |
| SCHEMBL1120884 | 0.84 | KDM4E (0.40) | NR3C1PGRNR3C2AR | |
| SCHEMBL1120782 | 0.80 | NR3C1 (0.39) | NR3C1PGRNR3C2AR | |
| SCHEMBL1120929 | 0.80 | KDM4E (0.45) | NR3C1PGRNR3C2ARSMN1; SMN2 | |
| SCHEMBL1120796 | 0.78 | NR3C1 (0.43) | NR3C1PGRNR3C2AR | |
| SCHEMBL4484871 | 0.78 | KDM4E (0.44) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935882-B1 | Bicyclic compounds | ASAHI KASEI PHARMA CORP (JP) | 2011-02-09 | — | — | EP | claimed |
| EP-1935882-B1 | Bicyclic compounds | ASAHI KASEI PHARMA CORP (JP) | 2011-02-09 | — | — | EP | disclosed |
| US-7511069-B2 | Indazole compounds as β3 andrenoceptor agonist | ASAHI PHARMA CORPORATION (JP) | 2009-03-31 | — | — | US | disclosed |