Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TGM2 | P21980 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19699681 | 0.81 | TGM2 (0.54) | LMNATGM2F13A1TGM1TGM3 | |
| SCHEMBL27801542 | 0.78 | TGM2 (0.58) | GAALMNATGM2F13A1TGM1 | |
| SCHEMBL16053417 | 0.77 | TGM2 (0.64) | LMNATGM2F13A1TGM1TGM3 | |
| SCHEMBL8177964 | 0.77 | GAA (0.70) | GAAHTTLMNACA1CA2 | |
| SCHEMBL19699400 | 0.76 | TGM2 (0.49) | LMNATGM2F13A1TGM1TGM3 | |
| SCHEMBL11802286 | 0.76 | TGM2 (0.47) | GAAHTTLMNATGM2CA1 | |
| SCHEMBL11521033 | 0.74 | GAA (0.45) | GAALMNATGM2F13A1TGM1 | |
| Acrylic Acid SCHEMBL30923509 | 0.74 | CA1 (0.50) | GAAHTTLMNACA1CA2 | |
| SCHEMBL22512392 | 0.74 | GAA (1.00) | GAAHTTLMNACA1CA2 | |
| SCHEMBL13921963 | 0.74 | TGM2 (0.55) | LMNATGM2F13A1TGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028999-B1 | PROCESS FOR THE PREPARATION OF ANTIOXIDANT AMIDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-03-23 | — | — | EP | disclosed |
| US-4286105-A | AMIDATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-08-25 | — | — | US | disclosed |
| EP-0028999-A1 | Process for the preparation of antioxidant amides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-05-20 | — | — | EP | disclosed |