Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4B | O94953 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL27561511 | 1.00 | GPR142 (0.38) | GPR142ALDH1A1KDM4AKDM4BKDM5C | |
| Imidazole SCHEMBL9152956 | 1.00 | GPR142 (0.38) | GPR142ALDH1A1KDM4AKDM4BKDM5C | |
| Imidazole SCHEMBL27609343 | 0.99 | GPR142 (0.38) | GPR142ALDH1A1KDM4AKDM4BKDM5C | |
| SCHEMBL466341 | 0.91 | GAA (0.40) | GPR142ALDH1A1GAAMAPTPOLB | |
| SCHEMBL1643961 | 0.91 | GAA (0.40) | GPR142ALDH1A1GAAMAPTPOLB | |
| SCHEMBL466340 | 0.91 | GAA (0.40) | GPR142ALDH1A1GAAMAPTPOLB | |
| Imidazole SCHEMBL27889109 | 0.88 | GPR142 (0.39) | GPR142RAB9A | |
| Imidazole SCHEMBL7422560 | 0.81 | NR1H4 (0.37) | GPR142RAB9A | |
| SCHEMBL6384640 | 0.81 | MC5R (0.39) | GPR142 | |
| SCHEMBL6447871 | 0.79 | SIRT2 (0.48) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021620-B1 | WATER-SOLUBLE PEPTIDES AFFECTING GONADAL FUNCTION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1983-02-23 | — | — | EP | disclosed |
| US-4244946-A | LUTEINIZING-HORMONE RELEASING FACTOR AGONISTS AS ANTIFERTILITY AGENTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1981-01-13 | — | — | US | disclosed |
| EP-0021620-A1 | Water-soluble peptides affecting gonadal function | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1981-01-07 | — | — | EP | disclosed |