Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212520 | 0.81 | NFE2L2 (0.46) | KDM4EPKML3MBTL1NFE2L2RAB9A | |
| SCHEMBL11114753 | 0.77 | SLC6A2 (0.44) | KDM4EPKML3MBTL1THRBNFE2L2 | |
| SCHEMBL819454 | 0.76 | KDM4E (0.46) | KDM4EPKML3MBTL1THRBNFE2L2 | |
| SCHEMBL30565846 | 0.73 | KDM4E (0.43) | KDM4EPKML3MBTL1THRBNFE2L2 | |
| SCHEMBL4004508 | 0.73 | KDM4E (0.43) | KDM4EPKML3MBTL1THRBNFE2L2 | |
| SCHEMBL27595256 | 0.72 | KDM4E (0.37) | KDM4EPKML3MBTL1THRBNFE2L2 | |
| Hydrochloric Acid SCHEMBL4005395 | 0.71 | KDM4E (0.42) | KDM4EPKML3MBTL1THRBNFE2L2 | |
| SCHEMBL6608142 | 0.71 | CYP1A2 (0.45) | KDM4EPKML3MBTL1NFE2L2ALDH1A1 | |
| SCHEMBL24214151 | 0.70 | ALOX5AP (0.43) | KDM4EPKML3MBTL1NFE2L2ALDH1A1 | |
| SCHEMBL28925088 | 0.70 | KDM4E (0.41) | KDM4EPKML3MBTL1NFE2L2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079154-A2 | 2-Ethylsulfonyl pyridine 1-oxide derivatives | UNIROYAL, INC. (US) | 1983-05-18 | — | — | EP | claimed |