⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665080 | 0.76 | FDPS (0.30) | — | |
| Phosphoric Acid SCHEMBL4948011 | 0.65 | KDM4E (0.32) | — | |
| Phosphoric Acid SCHEMBL4953743 | 0.65 | KDM4E (0.32) | — | |
| Phosphoric Acid SCHEMBL28813696 | 0.63 | EPHX1 (0.31) | — | |
| SCHEMBL13129928 | 0.63 | — | — | |
| SCHEMBL5165733 | 0.58 | — | — | |
| SCHEMBL9191419 | 0.58 | — | — | |
| SCHEMBL1792942 | 0.58 | — | — | |
| SCHEMBL2031403 | 0.57 | EPHX1 (0.32) | — | |
| SCHEMBL50056 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129660-A | Derivatives of cis-epoxy-1,2-propyl-phosphonic acid and drugs containing in particular as active ingredients derivatives of cis-epoxy-1,2-propylphosphonic acid in dextrorotatory form | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1978-12-12 | — | — | US | claimed |
| CN-104971378-A | FOSFOMYCIN PREPARATION, A METHOD FOR THE MANUFACTURE OF THE PREPARATION AND A PREPARATION-CONTAINING POLYMETHYLMETHACRYLATE BONE CEMENT POWDER | HERAEUS MEDICAL GMBH | 2015-10-14 | — | — | CN | disclosed |
| EP-0094815-A2 | Oligopeptide prodrugs | SMITHKLINE BECKMAN CORPORATION (US) | 1983-11-23 | — | — | EP | disclosed |
| US-4129660-A | Derivatives of cis-epoxy-1,2-propyl-phosphonic acid and drugs containing in particular as active ingredients derivatives of cis-epoxy-1,2-propylphosphonic acid in dextrorotatory form | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1978-12-12 | — | — | US | disclosed |
| US-4129660-A | Derivatives of cis-epoxy-1,2-propyl-phosphonic acid and drugs containing in particular as active ingredients derivatives of cis-epoxy-1,2-propylphosphonic acid in dextrorotatory form | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1978-12-12 | — | — | US | disclosed |
| US-4129660-A | Derivatives of cis-epoxy-1,2-propyl-phosphonic acid and drugs containing in particular as active ingredients derivatives of cis-epoxy-1,2-propylphosphonic acid in dextrorotatory form | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1978-12-12 | — | — | US | disclosed |