Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21879666 | 0.94 | ELANE (0.58) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL21879675 | 0.92 | ELANE (0.57) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL26545208 | 0.90 | ELANE (0.63) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL21879668 | 0.89 | ELANE (0.54) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL29255745 | 0.88 | ELANE (0.53) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL3168823 | 0.85 | ELANE (0.64) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL30877912 | 0.83 | ELANE (0.57) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL3166172 | 0.82 | SMN1; SMN2 (0.69) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL26038607 | 0.82 | KMT2A (0.69) | ELANEPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL21879669 | 0.81 | SMN1; SMN2 (0.47) | ELANEPOLBSMN1; SMN2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391731-A | Hydrogenated naphthalenes | HOFFMANN-LA ROCHE INC. (US) | 1983-07-05 | — | — | US | disclosed |