SCHEMBL3166172

SCHEMBL3166172

O=C(Oc1ccccc1)C1CCCC(C(=O)Oc2ccccc2)C1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.69
KMT2A Q03164 3/20 0.69
HTT P42858 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
ELANE P08246 2/20 0.59
POLB P06746 2/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
ALDH1A1 P00352 4/20 0.47
RAB9A P51151 2/20 0.47
HPGD P15428 1/20 0.44
PDGFRB P09619 1/20 0.44
PDGFRA P16234 1/20 0.44
MAPT P10636 2/20 0.43
GAA P10253 1/20 0.42
NPC1 O15118 1/20 0.42
PKM P14618 1/20 0.42
EPHX2 P34913 1/20 0.42
MEN1 O00255 1/20 0.42
SLC6A3 Q01959 1/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7866291 0.95 SMN1; SMN2 (0.62) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL3168823 0.92 ELANE (0.64) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL10778406 0.92 KMT2A (0.81) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL30877912 0.90 ELANE (0.57) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL30877928 0.89 KMT2A (0.74) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL9232274 0.89 KMT2A (0.74) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL3175349 0.88 ELANE (0.58) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL27617914 0.88 ELANE (0.58) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL7866274 0.87 ELANE (0.58) SMN1; SMN2KMT2AHTTTDP1ELANE
SCHEMBL234456 0.87 POLB (0.76) SMN1; SMN2KMT2AHTTTDP1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1587681-B1 A FORMABLE THERMOPLASTIC LAMINATE, A FORMED LAMINATE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-06-08 EP disclosed
CN-1756660-B A formable thermoplastic laminate, a formed laminate, an article, and a method of making an article SABIC INNOVATIVE PLASTICS IP 2010-10-27 CN disclosed
WO-2010005671-A1 A FORMABLE THERMOPLASTIC MULTI-LAYER ARTICLE, A FORMED MULTI-LAYER ARTICLE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-14 WO disclosed
US-20100009207-A1 FORMABLE THERMOPLASTIC MULTI-LAYER ARTICLE, A FORMED MULTI-LAYER ARTICLE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-14 US disclosed
EP-0719816-B2 Preparing method of polycarbonate GEN ELECTRIC (US) 2009-12-02 EP disclosed
EP-1116751-B1 POLYCARBONATE RESIN COMPOSITION, OPTICAL RECORDING MEDIUM, AND SUBSTRATE THEREFOR TEIJIN LTD (JP) 2009-07-29 EP disclosed
US-7514147-B2 Formable thermoplastic multi-layer laminate, a formed multi-layer laminate, an article, and a method of making an article SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-04-07 US disclosed
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP disclosed
US-7112645-B2 polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate GENERAL ELECTRIC COMPANY (US) 2006-09-26 US disclosed
CN-1250646-C Polycarbonate resin composition, optical recording medium, and substrate therefor TEIJIN LTD (JP) 2006-04-12 CN disclosed
US-5306801-A Heat resistance, hue stability, water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-04-26 US disclosed
US-5286834-A Condensing bisphenol A and biphenol with a carbonate diester GE PLASTICS JAPAN, LTD. (JP) 1994-02-15 US disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0572225-A1 Polycarbonate containing thermosetting resin compositions with low shrinkage GE PLASTICS JAPAN LIMITED (JP) 1993-12-01 EP disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0544407-A1 Copolymeric polycarbonates GE PLASTICS JAPAN LIMITED (JP) 1993-06-02 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
EP-0520805-A2 Polycarbonate production method GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed