SCHEMBL11209442

SCHEMBL11209442

Cc1ccc(N(O)c2ccc(C)c3ccccc23)c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.59
CYP2A6 P11509 3/20 0.46
EP300 Q09472 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT8 Q9H7Z6 1/20 0.41
ALDH1A1 P00352 1/20 0.39
CHEK1 O14757 1/20 0.38
NEK2 P51955 1/20 0.38
LIMK1 P53667 1/20 0.38
DYRK1A Q13627 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
TSHR P16473 2/20 0.37
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
HTT P42858 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10053554 0.81 CYP1A2 (0.65) CYP1A2CYP2A6EP300KAT2BKAT8
SCHEMBL29862285 0.79 CYP1A2 (0.62) CYP1A2CYP2A6EP300KAT2BKAT8
SCHEMBL1755244 0.79 CYP1A2 (0.62) CYP1A2CYP2A6EP300KAT2BKAT8
SCHEMBL18552312 0.77 CYP1A2 (0.59) CYP1A2CYP2A6EP300KAT2BKAT8
SCHEMBL29447796 0.77 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1TSHRGRIN2D
SCHEMBL29363045 0.77 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1TSHRGRIN2D
SCHEMBL161370 0.77 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1TSHRGRIN2D
SCHEMBL18552314 0.76 CYP1A2 (0.56) CYP1A2CYP2A6EP300KAT2BKAT8
SCHEMBL5503340 0.74 CYP1A2 (0.54) CYP1A2CYP2A6EP300KAT2BKAT8
SCHEMBL10053533 0.74 CYP1A2 (0.54) CYP1A2CYP2A6EP300KAT2BKAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046271-B1 PHOTOSENSITIVE COMPOSITIONS AND ELEMENTS CONTAINING SUBSTITUTED HYDROXYLAMINE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-10-19 EP disclosed
EP-0046271-A1 Photosensitive compositions and elements containing substituted hydroxylamine E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-24 EP disclosed
US-4298678-A PHOTOOXIDANT AND LEUCO DYE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-03 US disclosed