SCHEMBL10053533

SCHEMBL10053533

Cc1ccc(N(c2ccccc2)c2ccc(C)c3ccccc23)c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.54
CYP2A6 P11509 3/20 0.42
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CHEK1 O14757 1/20 0.35
NEK2 P51955 1/20 0.35
LIMK1 P53667 1/20 0.35
DYRK1A Q13627 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
TSHR P16473 3/20 0.34
EP300 Q09472 1/20 0.34
KAT2B Q92831 1/20 0.34
KAT8 Q9H7Z6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394113 0.96 CYP1A2 (0.54) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL19660700 0.90 CYP1A2 (0.48) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL1455840 0.90 CYP1A2 (0.48) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL13367504 0.89 CYP2A6 (0.47) CYP1A2CYP2A6ALDH1A1CYP3A4CYP2D6
SCHEMBL13868380 0.89 CYP1A2 (0.46) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL1455714 0.89 CYP1A2 (0.46) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL12262924 0.87 CYP1A2 (0.45) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL14018317 0.87 CYP1A2 (0.45) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL10053554 0.87 CYP1A2 (0.65) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL13367583 0.86 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2469341-B1 Image bearing member and image forming method, image forming apparatus, and process cartridge RICOH CO LTD (JP) 2016-03-30 EP disclosed
US-8652717-B2 Image bearing member and image forming method, image forming apparatus, and process cartridge using the same RICOH COMPANY, LTD. (JP) 2014-02-18 US disclosed
US-8652717-B2 Image bearing member and image forming method, image forming apparatus, and process cartridge using the same RICOH COMPANY, LTD. (JP) 2014-02-18 US disclosed
US-20120163860-A1 IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2012-06-28 US disclosed
US-20120163860-A1 IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2012-06-28 US disclosed
EP-2469341-A1 Image bearing member and image forming method, image forming apparatus, and process cartridge Ricoh Company, Ltd. (JP) 2012-06-27 EP disclosed
EP-2067808-B1 New polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL CO (JP) 2011-10-05 EP disclosed
EP-2067807-B1 New polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL CO (JP) 2011-07-06 EP disclosed
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 US disclosed
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 US disclosed
EP-1318163-B1 New polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL CO (JP) 2010-01-27 EP disclosed
EP-2067807-A1 New polymer and polymer light-emitting device using the same Sumitomo Chemical Company, Limited (JP) 2009-06-10 EP disclosed
EP-2067808-A1 New polymer and polymer light-emitting device using the same Sumitomo Chemical Company, Limited (JP) 2009-06-10 EP disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 US disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME CRY1, ARCN1, CORO1A CYP1A2 2208/4885CYP2A6 3039/4885ALDH1A1 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.