Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20368835 | 0.81 | MEN1 (0.56) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL95552 | 0.80 | MEN1 (0.62) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL3656132 | 0.77 | MEN1 (0.52) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL13379568 | 0.75 | CYP19A1 (0.67) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL197202 | 0.75 | MEN1 (0.62) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL2768675 | 0.75 | MEN1 (0.62) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL1538386 | 0.75 | MEN1 (0.62) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL31497682 | 0.75 | MEN1 (0.62) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL677101 | 0.72 | MEN1 (0.59) | KMT2AMEN1CYP19A1TSHRMAPK1 | |
| SCHEMBL8322314 | 0.72 | MEN1 (0.59) | KMT2AMEN1CYP19A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076722-A1 | Process for the preparation of alpha-aryl-propionic acids and their alkaline salts | Montedison S.p.A. (IT) | 1983-04-13 | — | — | EP | disclosed |