SCHEMBL197202

SCHEMBL197202

CC(C)(C)c1ccc(Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
POLB P06746 1/20 0.61
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
TSHR P16473 2/20 0.55
LMNA P02545 2/20 0.52
TYR P14679 1/20 0.52
CYP2A6 P11509 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
CYP19A1 P11511 2/20 0.48
MAPK1 P28482 1/20 0.48
HIF1A Q16665 1/20 0.48
NPSR1 Q6W5P4 1/20 0.45
HSD11B1 P28845 2/20 0.44
KIF11 P52732 1/20 0.44
CNR1 P21554 2/20 0.43
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2974451 0.97 POLB (0.59) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL5049965 0.92 KIF11 (0.56) MEN1KMT2APOLBNPC1RAB9A
Carbon Monoxide SCHEMBL10627118 0.89 POLB (0.59) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL11856617 0.89 POLB (0.53) MEN1KMT2APOLBNPC1RAB9A
Parachlorophenol SCHEMBL6904236 0.87 LMNA (0.76) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL10204685 0.85 RAB9A (0.63) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL6343251 0.85 POLB (0.50) MEN1KMT2APOLBNPC1RAB9A
Formic Acid SCHEMBL31540153 0.85 POLB (0.60) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL16326820 0.85 POLB (0.50) MEN1KMT2APOLBNPC1RAB9A
O-Xylene SCHEMBL28923128 0.85 POLB (0.50) MEN1KMT2APOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026849-A Method for continuously preparing 2, 6-binitro-p-tert-butyl chlorobenzene 孙有涛 2024-05-14 CN claimed
CN-115745457-A High-adaptability concrete superplasticizer, preparation method and application thereof 南京博特新材料有限公司 2023-03-07 CN claimed
CN-115725035-A Slump-retaining concrete superplasticizer, preparation method and application thereof 博特新材料泰州有限公司 2023-03-03 CN claimed
CN-109053491-A Synthetic method of the acaricide cyflumetofen intermediate to tert-butyl benzene acetonitrile 山东省农药科学研究院 2018-12-21 CN claimed
CN-105906564-B Compound, preparation method and its usage 海南省药物研究所 2018-11-30 CN claimed
US-8394541-B2 Lithium secondary battery and non-aqueous electrolytic solution UBE INDUSTRIES, LTD. (JP) 2013-03-12 US claimed
US-20110250504-A1 LITHIUM SECONDARY BATTERY AND NON-AQUEOUS ELECTROLYTIC SOLUTION UBE INDUSTRIES, LTD. (JP) 2011-10-13 US claimed
CN-116730879-B Method for selectively synthesizing 4-amino-N- (hetero) aryl sulfonamide compound SHAANXI NORMAL UNIVERSITY (CN) 2026-05-26 CN disclosed
WO-2025073702-A1 PROCESS FOR PREPARING AROMATIC AMINES FROM ARYL CHLORIDES BASF SE (DE) 2025-04-10 WO disclosed
US-12043613-B2 Inhibitors of SARM1 DISARM THERAPEUTICS, INC. (US) 2024-07-23 US disclosed
US-12043613-B2 Inhibitors of SARM1 DISARM THERAPEUTICS, INC. (US) 2024-07-23 US disclosed
US-20240228490-A1 HETEROCYCLIC DERIVATIVE INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2024-07-11 US disclosed
US-20240228490-A1 HETEROCYCLIC DERIVATIVE INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2024-07-11 US disclosed
EP-0368063-A1 Process for the chlorination in the nucleus of aromatic hydrocarbons BAYER AG (DE) 1990-05-16 EP disclosed
US-4851596-A Process for nucleus-chlorination of aromatic hydrocarbons BAYER AKTIENGESELLSCHAFT (DE) 1989-07-25 US disclosed
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed
US-4570005-A REACTING THE ARYL PROPYL CHLORIDE WITH THE CORRESPONDING ARYL ALCOHOL OR ARYL MERCAPTAN MITSUITOATSU CHEMICALS INC. (JP) 1986-02-11 US disclosed
US-4397864-A LOW TOXICITY MITSUITOATSU CHEMICALS INC. (JP) 1983-08-09 US disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 US disclosed
US-3941795-A ANTIHISTAMINE, ANTIALLERGY, BRONCHODILATOR RICHARDSON-MERRELL INC. (US) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228490-A1 HETEROCYCLIC DERIVATIVE INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF WEE1, CYP51A1, WEE2 MEN1 336/4885KMT2A 3536/4885POLB 2995/4885
US-12043613-B2 Inhibitors of SARM1 SARM1, SMN1; SMN2, SARNP MEN1 4363/4885KMT2A 3434/4885POLB 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.