SCHEMBL11209510

SCHEMBL11209510

CC(C[Si](Cl)(Cl)CC(C)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.52
AOC3 Q16853 2/20 0.52
TRPA1 O75762 4/20 0.45
RIPK1 Q13546 1/20 0.45
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
NISCH Q9Y2I1 3/20 0.41
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5413664 0.86 TAAR1 (0.52) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL9228189 0.86 AOC3 (0.44) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL9081434 0.86 AOC3 (0.44) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL9080403 0.85 AOC3 (0.43) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL1599405 0.84 TAAR1 (0.50) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL9230466 0.83 TAAR1 (0.42) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL8505708 0.83 AOC3 (0.42) TAAR1AOC3TRPA1RIPK1
SCHEMBL9080321 0.80 AOC3 (0.40) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL8506410 0.80 TAAR1 (0.40) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL9081242 0.80 AOC3 (0.40) TAAR1AOC3TRPA1RIPK1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4269993-A Diaralkyldichlorosilanes CHISSO CORPORATION (JP) 1981-05-26 US claimed
EP-0028665-A1 Process for the production of diaralkyldichlorosilanes and their use in manufacture of polysiloxane Chisso Corporation (JP) 1981-05-20 EP claimed
JP-54151952-A None JP disclosed
EP-0028665-B1 PROCESS FOR THE PRODUCTION OF DIARALKYLDICHLOROSILANES AND THEIR USE IN MANUFACTURE OF POLYSILOXANE Chisso Corporation (JP) 1983-05-18 EP disclosed
US-4269993-A Diaralkyldichlorosilanes CHISSO CORPORATION (JP) 1981-05-26 US disclosed
EP-0028665-A1 Process for the production of diaralkyldichlorosilanes and their use in manufacture of polysiloxane Chisso Corporation (JP) 1981-05-20 EP disclosed
JP-S54151952-A DIARALKYLDICHLOROSILANE CHISSO CORP 1979-11-29 JP disclosed