SCHEMBL5413664

SCHEMBL5413664

CC(C[Si](Cl)(Cl)Cl)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.52
AOC3 Q16853 2/20 0.52
TRPA1 O75762 4/20 0.45
RIPK1 Q13546 1/20 0.45
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
NISCH Q9Y2I1 3/20 0.41
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5490777 0.88 GRIA4 (0.46) TAAR1AOC3
SCHEMBL11209510 0.86 TAAR1 (0.52) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL1599405 0.84 TAAR1 (0.50) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL5488878 0.83 LTA4H (0.43) TSHR
SCHEMBL5490217 0.82 IDO1 (0.38) AOC3NISCH
SCHEMBL5494536 0.80 ACHE (0.44) AOC3TSHRALDH1A1
SCHEMBL5484319 0.80 ADRB2 (0.46) AOC3TSHR
SCHEMBL5485069 0.79 HDAC4 (0.39) AOC3TSHRALDH1A1
SCHEMBL14788539 0.79 TAAR1 (0.54) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL16550650 0.79 TAAR1 (0.54) TAAR1AOC3TRPA1RIPK1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119144685-B Method for preparing dendrobium candidum peptide by enzymolysis method 江西轩斛轩健康科技有限公司 2025-05-09 CN claimed
CN-119144685-A Method for preparing dendrobium candidum peptide by enzymolysis method 江西轩斛轩健康科技有限公司 2024-12-17 CN claimed
US-5113001-A Process for preparing sulfophenylalkylsiloxanes or sulfonaphthylalkylsiloxanes BASF CORPORATION (US) 1992-05-12 US claimed
CN-119144685-B Method for preparing dendrobium candidum peptide by enzymolysis method 江西轩斛轩健康科技有限公司 2025-05-09 CN disclosed
CN-119144685-A Method for preparing dendrobium candidum peptide by enzymolysis method 江西轩斛轩健康科技有限公司 2024-12-17 CN disclosed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-7229729-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MONOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-06-12 US disclosed
US-20050037274-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2005-02-17 US disclosed
US-6797444-B2 A PROTECTIVE LAYER CONTAINING A COUPLING FLUOROPOLYMER PARTICLES DISPERSED IN A COPOLYMER HAVING A FLUORINE ATOM-CONTAINING SILOXANE ADDITION-CONDENSATION PRODUCT IN A SIDE CHAIN; NONABRASIVE, HARDENING KONICA CORPORATION (JP) 2004-09-28 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed
US-20030134209-A1 Electrophotographic photoreceptor and production method of the same KONICA CORPORATION (JP) 2003-07-17 US disclosed
US-6569586-B2 Comprises photosensitive layer and resin layer including organic polymer, siloxane component, and charge transfer component; durability KONICA CORPORATION (JP) 2003-05-27 US disclosed
US-20020076631-A1 Photoreceptor for forming electrostatic latent image KONICA CORPORATION (JP) 2002-06-20 US disclosed
US-5622784-A WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM SEIKO EPSON CORPORATION (JP) 1997-04-22 US disclosed
EP-0646616-B1 Organopolysiloxanes having bifunctional siloxane end groups WACKER CHEMIE GMBH (DE) 1997-03-05 EP disclosed
US-5527935-A Organopolysiloxanes having bifunctional terminal siloxane units WACKER-CHEMIE GMBH (DE) 1996-06-18 US disclosed
EP-0646616-A1 Organopolysiloxanes having bifunctional siloxane end groups Wacker-Chemie GmbH (DE) 1995-04-05 EP disclosed
US-5386050-A (2-arylpropyl)alkylsilanes and their preparation methods KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1995-01-31 US disclosed
US-5113001-A Process for preparing sulfophenylalkylsiloxanes or sulfonaphthylalkylsiloxanes BASF CORPORATION (US) 1992-05-12 US disclosed