Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.71 |
| ▸ | CTSL | P07711 | 9/20 | 0.71 |
| ▸ | CTSS | P25774 | 6/20 | 0.71 |
| ▸ | CTSB | P07858 | 1/20 | 0.69 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.62 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014223 | 1.00 | CTSK (0.71) | CTSKCTSLCTSSCTSBPSMB1 | |
| SCHEMBL7618462 | 0.93 | CTSK (0.74) | CTSKCTSLCTSSCTSB | |
| SCHEMBL20609249 | 0.92 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL20609250 | 0.92 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL3959352 | 0.90 | CTSK (0.61) | CTSKCTSLCTSSCTSB | |
| SCHEMBL2147583 | 0.90 | CTSK (0.61) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4660369 | 0.90 | CTSK (0.61) | CTSKCTSLCTSSCTSB | |
| SCHEMBL10610800 | 0.89 | CTSK (0.63) | CTSKCTSLCTSSCTSB | |
| SCHEMBL10610794 | 0.89 | CTSK (0.63) | CTSKCTSLCTSSCTSB | |
| SCHEMBL20609256 | 0.88 | CTSK (0.71) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040435-B1 | PEPTIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Eisai Co., Ltd. (JP) | 1983-07-20 | — | — | EP | claimed |
| EP-0040435-A1 | Peptide derivatives and process for the preparation thereof | Eisai Co., Ltd. (JP) | 1981-11-25 | — | — | EP | claimed |
| EP-0040435-B1 | PEPTIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Eisai Co., Ltd. (JP) | 1983-07-20 | — | — | EP | disclosed |
| EP-0040435-A1 | Peptide derivatives and process for the preparation thereof | Eisai Co., Ltd. (JP) | 1981-11-25 | — | — | EP | disclosed |