Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479722 | 0.89 | PTGS1 (0.42) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL8577668 | 0.87 | PTGS1 (0.57) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL10686594 | 0.87 | PTGS1 (0.57) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL10550089 | 0.87 | PTGS1 (0.57) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL11142983 | 0.85 | PTGS1 (0.44) | PTGS1MEN1KMT2ACYP2D6FNTA | |
| SCHEMBL11248942 | 0.85 | TSHR (0.44) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL10976289 | 0.85 | PTGS1 (0.44) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL10507535 | 0.85 | TSHR (0.44) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL10507529 | 0.85 | TSHR (0.44) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL11491256 | 0.84 | SCN9A (0.38) | MEN1KMT2AALOX5SCN9AFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150207-A1 | USE OF CYCLOPROPANECARBOXYLIC ACID ESTER DERIVATIVES FOR CONTROLLING INSECTICIDE-RESISTANT INSECTS | BAYER CROPSCIENCE AG (DE) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012150206-A2 | NOVEL CYCLOPROPANOIC ACID ESTER DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-11-08 | — | — | WO | disclosed |
| US-4336266-A | Insecticidal 2,2-dimethyl-3-(2',2'-dihalovinyl)-cyclopropane carboxylic acid 3-halophenoxy-α-vinylbenzyl esters | CIBA-GEIGY CORPORATION (US) | 1982-06-22 | — | — | US | disclosed |
| US-4242357-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |