Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.40 |
| ▸ | GLI2 | P10070 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686594 | 1.00 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL10550089 | 1.00 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| Alcohol SCHEMBL11147915 | 0.92 | PTGS1 (0.54) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL11209682 | 0.87 | PTGS1 (0.44) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL11142983 | 0.87 | PTGS1 (0.44) | PTGS1MEN1CYP2D6KMT2AMAOB | |
| SCHEMBL10976289 | 0.87 | PTGS1 (0.44) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL11469906 | 0.85 | FNTA (0.43) | PTGS1MEN1CYP2D6KMT2AAKR1C3 | |
| SCHEMBL11479722 | 0.85 | PTGS1 (0.42) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL6965069 | 0.84 | SRD5A2 (0.54) | PTGS1LTA4HTSHRSRD5A2NR1H2 | |
| SCHEMBL1677135 | 0.83 | TSHR (0.60) | PTGS1MEN1CYP2D6KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661488-A | Pyrimidine substituted-2,2-dimethylcyclopropane carboxylates useful for combating insect and acarine pests at a locus | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-28 | — | — | US | claimed |
| EP-0162538-A2 | Cyclopropane derivates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-27 | — | — | EP | claimed |
| US-4423243-A | Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropanecarboxylic acids and esters | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | claimed |
| US-4225503-A | Manufacture of esters | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-09-30 | — | — | US | claimed |
| JP-55167254-A | — | — | None | — | — | JP | disclosed |
| JP-56057740-A | — | — | None | — | — | JP | disclosed |
| WO-2013111393-A1 | HAIR GROWING AGENT | 学校法人東海大学 (JP) | 2013-08-01 | — | — | WO | disclosed |
| WO-1998018329-A1 | ARTHROPODICIDES AND PROCESS FOR THEIR PREPARATION | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1998-05-07 | — | — | WO | disclosed |
| EP-0317265-B1 | Novel imidate insecticides | ZENECA INC (US) | 1994-06-01 | — | — | EP | disclosed |
| WO-1994008931-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF SUBSTITUTED 2-PHENYL-5-(3-PHENOXYPHENYL)-1,1,1-TRIFLUOROPENTANES | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |
| US-5089623-A | Certain imidate insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-4087523-A | 2,2-DIMETHYL-4,5-BENZOSPIRO(2,4)HEPTA-4,6-DIENE-1-CARBOXYLIC ACID, ALPHA-CYANO-M-PHENOXYBENZYL ESTER; N'-(4-CHLORO-O-TOLYL)-N,N-DIMETHYLFORMAMIDINE | AMERICAN CYANAMID COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4060632-A | MITICIDE, 3,3'-DIMETHYLSPIRO(CYCLOPROPANE-1,1'-INDENE-2-CARBOXYLIC ACID, M-PHENOXYBENZYL ESTERS | AMERICAN CYANAMID COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4056628-A | Insecticidal esters of alpha-phenoxy alkanoic acids with substituted benzyl alcohols | HOFFMANN-LA ROCHE INC. (US) | 1977-11-01 | — | — | US | disclosed |
| US-4012522-A | INSECTICIDES | SHELL OIL COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-3998868-A | INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-12-21 | — | — | US | disclosed |
| US-3966959-A | Insecticidal and acaricidal, pyrethroid compounds | AMERICAN CYANAMID COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3962458-A | Systemic control of ectoparasites with pyrethroids | AMERICAN CYANAMID COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3954814-A | INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-05-04 | — | — | US | disclosed |