Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211515 | 0.85 | HSD17B10 (0.32) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL60677 | 0.85 | — | — | |
| SCHEMBL11214095 | 0.84 | TSHR (0.44) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL8576719 | 0.80 | MAPT (0.47) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL20504576 | 0.80 | ALDH1A1 (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL30673 | 0.79 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL988078 | 0.79 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL1132722 | 0.79 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL8636270 | 0.79 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL27130 | 0.79 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102271732-A | Nanochannel devices and related methods | — | 2011-12-07 | — | — | CN | disclosed |
| US-4398913-A | ALKALINE PASTES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |