Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18053741 | 0.91 | KMT2A (0.49) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL18053745 | 0.91 | KMT2A (0.49) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL15078762 | 0.90 | ALOX5 (0.48) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL17805709 | 0.89 | ALOX5 (0.47) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL16451181 | 0.89 | ALOX5 (0.47) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL29818747 | 0.89 | CYSLTR2 (0.56) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL2207435 | 0.89 | CYSLTR2 (0.56) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL19291629 | 0.89 | CYSLTR2 (0.56) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL15016887 | 0.88 | ALOX5 (0.56) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL19291557 | 0.87 | TSHR (0.55) | ALOX5TSHRCYSLTR2CYSLTR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024616-B1 | 1-(3'-ACYLOXYPHENYL)-2-AMINOETHANOLS, THEIR ACID ADDITION SALTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | Klinge Pharma GmbH (DE) | 1983-02-09 | — | — | EP | claimed |
| EP-0024616-B1 | 1-(3'-ACYLOXYPHENYL)-2-AMINOETHANOLS, THEIR ACID ADDITION SALTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | Klinge Pharma GmbH (DE) | 1983-02-09 | — | — | EP | disclosed |
| EP-0024616-A1 | 1-(3'-Acyloxyphenyl)-2-aminoethanols, their acid addition salts, pharmaceutical compositions containing them and process for their preparation | Klinge Pharma GmbH (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024616-A1 | 1-(3'-Acyloxyphenyl)-2-aminoethanols, their acid addition salts, pharmaceutical compositions containing them and process for their preparation | Klinge Pharma GmbH (DE) | 1981-03-11 | — | — | EP | disclosed |