Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442888 | 0.74 | CNR1 (0.44) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL30307890 | 0.74 | CNR1 (0.44) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL8684877 | 0.71 | MEN1 (0.46) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL8680342 | 0.69 | TSHR (0.53) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL8679953 | 0.65 | TSHR (0.62) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL8681146 | 0.65 | MEN1 (0.62) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL10751360 | 0.65 | MEN1 (0.37) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL8871056 | 0.63 | HTR2C (0.46) | MEN1TP53MAPTTSHRMAPK1 | |
| SCHEMBL9488195 | 0.61 | OPRM1 (0.36) | TSHR | |
| SCHEMBL1698175 | 0.61 | CA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334067-A | ANTICONVULASANTS, ANTIULCER AGENTS | MARUKO SEIYAKU CO., LTD. (JP) | 1982-06-08 | — | — | US | disclosed |